Biophysical characterization of synthetic amelogenin C-terminal peptides
نویسندگان
چکیده
منابع مشابه
Biophysical characterization of Abeta42 C-terminal fragments: inhibitors of Abeta42 neurotoxicity.
A key event in Alzheimer's disease (AD) is age-dependent, brain accumulation of amyloid beta-protein (Abeta) leading to Abeta self-association into neurotoxic oligomers. Previously, we showed that Abeta oligomerization and neurotoxicity could be inhibited by C-terminal fragments (CTFs) of Abeta42. Because these CTFs are highly hydrophobic, we asked if they themselves aggregated and, if so, what...
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ژورنال
عنوان ژورنال: European Journal of Oral Sciences
سال: 2012
ISSN: 0909-8836
DOI: 10.1111/j.1600-0722.2012.00941.x